Impact of Phenazine-1-carboxylic acid upon Biofilm Development in the Rhizosphere of Dryland and Irrigated Wheat

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Accumulation of the antibiotic phenazine-1-carboxylic acid in the rhizosphere of dryland cereals.

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Phenazine-1-carboxylic acid promotes bacterial biofilm development via ferrous iron acquisition.

The opportunistic pathogen Pseudomonas aeruginosa forms biofilms, which render it more resistant to antimicrobial agents. Levels of iron in excess of what is required for planktonic growth have been shown to promote biofilm formation, and therapies that interfere with ferric iron [Fe(III)] uptake combined with antibiotics may help treat P. aeruginosa infections. However, use of these therapies ...

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ژورنال

عنوان ژورنال: Microscopy and Microanalysis

سال: 2015

ISSN: 1431-9276,1435-8115

DOI: 10.1017/s1431927615004353